1.the general state of things; the combination of circumstances at a given time;
the present international situation is dangerous
2.a condition or position in which you find yourself;
the unpleasant situation (or position) of having to choose between two evils
3.a complex or critical or unusual difficulty;
the dangerous situation developed suddenly
4.physical position in relation to the surroundings;
the sites are determined by highly specific sequences of nucleotides
5.a job in an organization;
he occupied a post in the treasury